BDBM50014846 (S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide::(S)-colchicine::7alphaH-colchicine::CHEMBL107::COLCHICINE::N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide::colchicina::colchicinum
SMILES COc1cc2CC[C@H](NC(C)=O)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC
InChI Key InChIKey=IAKHMKGGTNLKSZ-INIZCTEOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 31 hits for monomerid = 50014846
Affinity DataKi: 1.60nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 5.75E+3nMAssay Description:Binding affinity against tubulin usingf [3H]-colchicine as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 3.79E+3nMAssay Description:Inhibition of porcine tubulin polymerization by UV-Vis microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.93E+4nMAssay Description:Concentration of compound required to inhibit tubulin polymerization (Microtubule assembly) was determined by the turbidity formation after 20 min of...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro tubulin polymerization-inhibitory activity.More data for this Ligand-Target Pair
Affinity DataIC50: 6.93E+3nMAssay Description:Inhibition of tubulin beta polymerization in human MCF7 cells after 18 to 24 hrs by ELISA based spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+3nMAssay Description:In vitro inhibitory concentration required to displace [3H]colchicine from its binding site on tubulinMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:In vitro inhibition of maximum porcine tubulin assembly rate after 20 min at 37 degrees CMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of tubulin polymerization in porcine brainMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization assessed as reduction in GTP-induced microtubule assembly after 60 mins by OD340 methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMAssay Description:Inhibition of porcine brain tubulin polymerization measured every 1 min for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of pig brain tubulin polymerization in presence of GTP by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 3.70E+3nMAssay Description:Binding affinity to porcine tubulin after 1 hr by spectrofluorometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.68E+3nMAssay Description:Inhibition of pig brain tubulin polymerization by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.06E+3nMAssay Description:Displacement of [3H]Colchicine from pig biotinylated tubulin after 2 hrs by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of pig tubulin polymerization determined after 45 mins at 37 degC by turbidimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of porcine brain tubulin polymerizationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.06E+3nMAssay Description:Displacement of [3H]colchicine from biotinylated pig brain tubulin after 2 hrs by competitive scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetry analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7.85E+3nMAssay Description:Binding affinity to pig brain tubulin polymerization measured every 1 mins of 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of pig brain tubulin polymerization measured every 1 min for 25 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKd: 1.13E+4nMAssay Description:Binding affinity to porcine brain tubulin polymerization by surface plasmon analysis analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization incubated for 60 mins by fluorescence-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of pig brain tubulin polymerization by spectrometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of pig brain tubulin polymerization in the presence of GTP by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of pig brain tubulin polymerization by spectrophotometeric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of pig brain tubulin polymerization by spectrometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of porcine brain tubulin polymerization preincubated for 1 mins followed by GTP addition and measured for 60 mins at 1 min interval by flu...More data for this Ligand-Target Pair